Standard Guide for Performance of Chinese Hamster Ovary Cell/Hypoxanthine Guanine Phosphoribosyl Transferase Gene Mutation Assay1. Scope 1. 1 This guide highlights some of the more relevant biological concepts as they are currently understood, and summarizes the critical technical aspects for acceptable bioassay performances as they currently are perceived and practiced. The Chinese hamster ovary cell hypoxanthine guanine phosphoribosyl transferase (CHO HGPRT) assay (1)2 has been widely applied to the toxicological evaluation of industrial and environmental chemicals.

Type 1 Below 1 in

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gearwheels or other components onto the axle

Convexity–Concavity

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This European Standard supersedes BS EN 61000-6-2:2001 which will be withdrawn on 1 June 2008

This document is applicable to all types of organization (for example

finished in an identical manner to the finished product and of a size sufficient to meet the requirements of the test

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1   Scope of application

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