Human IL-21 Protein (CHO) _ 90266ESInterleukin 18 (IL 18), a pro inflammatory cytokine belonging to the IL 1 superfamily, is produced by macrophages and other cells. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, T cells and phagocytes. Mature human IL 18 shares approximately 63% amino acid sequence identity with mouse and rat IL 18. Activation of IL 18 is induced by infection or tissue injury and leads to disease pathology in chronic

It is cleaved after the fourth Kringle domain by a serine protease to form bioactive disulfide-linked HGF with a 60 kDa alpha and 30 kDa beta chain

JC-10 shifts from a polymeric form to a monomeric form in the cytoplasm

Measured in a cell proliferation assay using TF-1 cells

Coomassie brilliant blue is widely available in G250 and R250

thus reinforcing peripheral tolerance and preventing development of autoimmunity

keeps the product in a high-temperature heating state

12906_Manual_HB220412

Hieff Unicon Hotstart Direct Taq DNA Polymerase is a hotstart DNA polymerase that is resistant to blood and other inhibitors

HACE1 negatively regulates neuroinflammation through ubiquitylating and degrading Rac1 in Parkinson's disease models

Biotinylated Human IL-2 R gamma/CD132 Protein is expressed from HEK293 with His tag and Avi tag at the C-terminal

2× Hieff™ FCD qPCR SYBR Master Mix*

This kit is based on super multiplex PCR